Multidrug Resistance Protein Interactions of Ofloxacin and Erythromycin
نویسندگان
چکیده
10.1128/AAC.44.6.1697-1700.2000. 2000, 44(6):1697. DOI: Antimicrob. Agents Chemother. Mitsuhiro Suenaga, Chuwa Tei and Shigeru Kohno Takashi Nakamura, Kazuhiro Tsukamoto, Yuji Noguchi, Shigeru Kawabata, Katsumi Nakatomi, Ken Shiozawa, Kenji Terashi, Mikio Oka, Hiroshi Soda, Minoru Fukuda, Leukemia Cells (MRP) in MRP-Overexpressing Human with the Multidrug Resistance Protein Interactions of Ofloxacin and Erythromycin
منابع مشابه
Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells.
To investigate interactions between the multidrug resistance protein (MRP) and antimicrobial agents, we examined the effects of 12 agents on vincristine sensitivity and efflux of the calcein acetoxy-methyl ester (calcein-AM) of a MRP substrate in MRP-overexpressing cells. Only ofloxacin and erythromycin enhanced sensitivity with increased intracellular vincristine accumulation and inhibited the...
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متن کاملبررسی فراوانی ژنهای magA، fimHو rmpA در بین سویههای کلبسیلا پنومونیه جداشده از بیماران بستری در بیمارستانهای شهرستان بابل
Background and Objective: Klebsiella pneumoniae is known as one of the opportunistic pathogens. The prevalence of antibiotic resistance, emergence of multidrug resistant strains, and multiple virulence factors contribute to the development of various infections. In this regard, the aim of this study was to evaluate the frequency of fimH, magA, and rmpA genes among Klebsiella pneumoniae isolates...
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